PHYSOSTIGMA VENENOSUM
Calabar Bean
This treatment and its lively principle, Eserine, shape a treasured addition to Materia Medica. Stimulates heart, raises blood pressure, and will increase peristalsis. Causes contraction of the student and of the ciliary muscles. Induces a circumstance of short-sightedness. Spinal irritation, loss of motility, prostration, with very touchy vertebrae Fibrillary tremors. Rigidity of muscles; paralysis. Depresses the motor and reflex pastime of the wire and reasons loss of sensibility to pain, muscular weakness, accompanied by using entire paralysis, even though muscular contractility is now not impaired. Paralysis and tremors, chorea. Meningeal irritation, with pressure of muscles. Tetanus and trismus. Polymyelitis anterior. Eserine is used regionally to produce contraction of pupil.
Head.–Constant ache on top; vertigo, with constrictive feeling of head. Pain over orbits; can’t endure to elevate eyelids. Cerebro-spinal meningitis; widespread tetanic rigidity. Spastic stipulations of the face-muscles.
Eyes.–Night-blindness (Opposite: Bothrops); photophobia; contraction of pupils; twitching of ocular muscles. Lagophthalmus. Muscae volitantes; flashes of light; partial blindness. Glaucoma; paresis of accommodation; astigmatism. Profuse lachrymation. Spasm of ciliary muscles, with irritability after the use of eyes. Increasing myopia. Post-diphtheritic paralysis of eye and lodging muscles.
Nose.–Fluent coryza; burning and tingling of nostrils; nostril stuffed and hot. Fever-blisters round nostrils.
Mouth.–Tongue feels sore on tip. Feeling as if a ball got here up throat.
Throat.–Strong heart-pulsation felt in throat.
Stomach.–Great ache right now after eating. Sensitive to stress in epigastric region. Pain extends into chest and down arms. Gastralgia; persistent constipation.
Female.–Irregular menstruation, with palpitation. Congestion of eyes. Rigid muscles.
Heart.–Feeble pulse; palpitation; spasmodic action, with feeling pulsation thru the total body. Beats of coronary heart quite perceptible in chest and head. Fluttering of coronary heart felt in throat. Fatty degeneration (Cup ac).
Extremities.–Pain in proper popliteal space. Burning and tingling in spine. Hands and ft numb. Sudden jerking of limbs on going to sleep. Tetanic convulsions. Locomotor ataxia. Numbness in paralyzed parts, crampy pains in limbs.
Relationship.–Compare: Eserine-the alkaloid of Physostigma–(slows motion of coronary heart and will increase arterial tension; in ciliary spasm and spasmodic astigmatism due to irregular motion of ciliary muscles; blepharo-spasms; students contracted. Twitching of lids, ache of eyeballs, blurring of imaginative and prescient after the usage of eyes, pains round eyes and head). Used regionally to contract the pupil. Eserine contracts the students dilated with the aid of Atropin, however no longer these dilated by using Gelsemium. Internally 6x.
Eserin Salicylate (post-operative intestinal paralysis; meteorism. Hypodermically 1/60-1/40 gr).
Compare also: Muscarin; Conium; Curare; Gels; Thebainum (tetanus); Piperazinum–(Uric acid conditions. Pruritus. Gout and urinary calculi. Constant backache. Skin dry, urine scanty. Rheumatic urthritis. Give one grain every day in carbonated water. First and 2nd decimal trituration three instances a day).
Antidote: Atropia. In full medicinal doses will relieve most of the outcomes of physostigmine.
Dose.–Third potency. The impartial sulphate of Eserine is instilled into the eye, from one-half to 4 grains to one ounce distilled water, to set off contraction of pupil, in mydriasis, accidents to the eye, iritis, corneal ulcers, etc.
