ANTIPYRINUM
Phenazone-A Coal-tar Derivative
(ANTIPYRINE)
Antipyrine is one of the pills that result in leucocytosis, comparable to ergotin, salicylates, and tuberculin. Acts particularly on the vaso-motor centers, inflicting dilation of capillaries of pores and skin and consequent circumscribed patches of hyperaemia and swelling. In giant doses reasons profuse perspiration, dizziness, cyanosis, and somnolence, albumen and blood in urine. Acute erythema multiforme.
Mind.–Fear of turning into insane; anxious anxiety; hallucinations of sight and hearing.
Head.–Throbbing headache; sensation of constriction. Flashes of heat. Headache underneath ears with earache.
Eyes.–Puffiness of lids. Conjunctiva purple and oedematous, with lachrymation. Red spots (Apis).
Ears.–Pains and buzzing. Tinnitus.
Face.–Å’dema and puffiness. Red and swollen.
Mouth.–Swelling of lips. Burning of mouth and gums. Ulceration of lips and tongue; vesicles and bullae. Small lump in cheek. Tongue swollen. Bloody saliva. Toothache alongside decrease jaw.
Throat.–Pain on swallowing. Expectoration of fetid pus. Abscess, white false membrane. Sensation of burning.
Stomach.–Nausea and vomiting; burning and pain.
Urine.–Diminished. Penis black.
Female.–Itching and burning in vagina. Menses suppressed. Watery leucorrhoea.
Respiratory.–Fluent coryza. Nasal mucous membrane swollen. Dull pains in frontal sinus. Aphonia. Oppression and dyspnoea. Cheyne-Stokes respiration.
Heart.–Faintness, with sensation of stoppage of heart. Throbbing for the duration of the body. Rapid, weak, irregular pulse.
Nerves.–Epileptiform seizures. Contractures. Trembling and cramps. Crawling and numbness. General prostration.
Skin.–Erythema, eczema, pemphigus. Intense pruritus. Urticaria, performing and disappearing suddenly, with interior coldness. Angioneurotic-oedema. Dark blotches on pores and skin of penis, once in a while with oedema.
Dose.–Second decimal potency.