SERUM ANGUILLAE
Eel Serum (SERUM ANGUILLAR ICHTHYOTOXIN)
The serum of the eel has a poisonous motion on the blood, swiftly destroying its globules. The presence of albumin and renal factors in the urine, the hemoglobinuria, the extended anuria (24 and 26 hours), collectively with the effects of the autopsy, it seems that show its optionally available motion on the kidneys. Secondarily, the liver and the coronary heart are affected, and the adjustments located are these generally current in infectious diseases.
From all these information it is effortless to infer, a priori, the therapeutical warning signs of the serum of the eel. Whenever the kidney will become acutely affected, both from bloodless or contamination or intoxication, and the assault is characterised via oliguria, anuria and albuminuria, we will locate the eel’s serum eminently efficacious to re-establish diuresis, and in swiftly arresting albuminuria. When at some point of the direction of heart-disease, the kidney, until now working well, need to abruptly come to be affected and its feature inhibited; and when except we take a look at cardiac irregularities and a marked nation of asystolia, we can also yet assume top outcomes from this serum. But to decide right here the preference of this treatment is no longer an handy matter. While digitalis affords in its indications, the accepted symptomatic trilogy: arterial hypertension oliguria and oedema; the serum of the eel appears higher tailored to instances of hypertension and oliguria, except oedema. We have to endure in thought that the non-obligatory motion of the eel’s serum is on the kidney, and I agree with we can nicely assert that if digitalis is a cardiac, the eel’s serum is a renal remedy. So far, at least, the medical observations posted appear to affirm this distinction. The serum of the eel has given very small effects in assaults of asystolia; however it has been very efficacious in cardiac uraemia. There, the place digitalis is powerless, the serum of the eel has put an stop to the renal obstruction and produced an considerable diuresis. But its in reality precise indication looks to be for acute nephritis a frigori (Jousset)
Subacute nephritis. Heart diseases, in instances of failure of compensation and impending asytole. The experiments of Dr. Jousset have amply proven the fast haematuria, albuminuria and oliguria prompted by using it. In the presence of acute nephritis with threatening uraemia we have to constantly assume of this serum. Very efficacious in useful coronary heart diseases. Mitral insufficiency, asystolia with or besides oedema, dyspnoea and tough urinary secretion.
Relationship.–Great analogy exists between eel serum and the venom of the Vipera.
Compare also: Pelias; Lachesis.
Dose.–Attenuations are made with glycerine or distilled water, the decrease 1x to three in coronary heart disease, the higher in surprising renal attacks.
